“For excellence in respiratory measurement”

John D. Brannan PhD

Clinical Respiratory Scientist

+61-435-206-232
(0435 206 232 within Australia)

About Me

A clinical respiratory scientist specialising in lung function measurement

“I want to advance respiratory measurement in the respiratory laboratory to advance lung disease with new innovations that will ultimately advance patient care……so that decision making and treatment choices are the best that science can currently offer”

I focus on measurement of respiratory disease

Fortunate to start training at a Center of Excellence, Royal Prince Alfred Hospital in Sydney under the supervision of Dr Sandra D. Anderson, I was pivotal in the development of the mannitol bronchial provocation test (Aridol/Osmohale) that has registration with leading regulatory authorities (e.g., FDA, TGA, EMA).

Following receiving my PhD in 2001 from the University of Sydney with my thesis titled “Osmotic challenge in asthma using a dry powder of mannitol” I played a key role in the technology transfer of this technology to Pharmaxis leading to the first regulatory authority guided Phase 3 study of a bronchial provocation test.

What I Do

I perform clinical testing in respiratory disease and participate in research with a focus on airway disease

Diagnosis of asthma

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Professional Experience

My Experience

From April 1995 to July 2005 : Research Fellw employed by Dr Sadra D. Anderson in the Department of Respiratory Medicine,Royal Prince Alfred Hospital, Camperdown,Australia; on grants from the National Health and Medical Research Coucil of Australia & funds awarded from the Royal Prince Alfred Research Prize.

From August 2005 to 2007 : Post Graduate Research Fellow employed by Professor Paul M. O’Byrne in the Asthma Research Unit, Firestone Institute of Respiratory Health, St Joseph’s Healthcare, Hamilton, Ontario,Canada; on the Asthma Foundation of New South Wales,Martin Hardie Traveling Fellowship.

From August 2007 to February 2009 : Senior Research Fellow employed by Professor Paul M. O’Byrne and Assoc Professor Parameswaran Nair in the Asthma Research Unit, Firestone Institute of Respiratory Health, St Joseph’s Healthcare, Hamilton, Ontario, Canada; funded by Department of Medicine, McMaster University

April 1995 to present : Pivotal in the development of dry powder mannitol for bronchial provocation to identify airway hyperresponsiveness and world expert on this methodology. Licensed to Pharmaxis Ltd., Australia, Aridol^™ or Osmohale^™ is now registered in 26 countries worldwide, including Australia and the European Union and the United States.

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Scientific Publications

Education

• Bachelor of Science (Biochemistry/Physiology) 1994 at the University of New South Wales, Kensington, NSW, Australia

Double Major: Physiology & Pharmacology, Molecular Biology & Biochemistry.

• Masters of Science in Medicine Honors Year 1997 – University of Sydney; 1st Class Honors equivalent (Mark; 85)

• Converted MSc to PhD 1998. Completed a PhD through the Department of Pharmacology/Faculty of Medicine, University of Sydney, under the supervision of Professor J.P Seale & Dr S.D Anderson.

PhD Thesis Title: “Osmotic challenge in asthma using dry power of mannitol”.

Accepted June 19^th, 2001.